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SUMMARY:Development and Commissioning of the KIT 3D Ultrasound Computed To
 mography System III
DTSTART:20260611T120000Z
DTEND:20260611T130000Z
DTSTAMP:20260617T093000Z
UID:indico-event-5652@indico.kit.edu
CONTACT:timo.muscheid@kit.edu
DESCRIPTION:Speakers: Michael Zapf (KIT/IPE)\n\nMichael Zapf has recently 
 submitted his PhD thesis and will present his results on 3D ultrasound com
 puter tomography.\nAbstract: \nThis dissertation presents the conception\
 , development\, and clinical evaluation of the third-generation three-dime
 nsional ultrasound computed tomography system (3D USCT) for early breast c
 ancer detection. The new setup was designed to address limitations identif
 ied in clinical studies of its predecessor\, including limited imaging vol
 ume\, breast-positioning variability\, patient motion during acquisition\,
  and workflow inefficiencies. The imaging region was expanded to 20 ×20 
 ×20 cm3\, and all major mechanical\, electronic\, and procedural subsyste
 ms were redesigned to improve robustness\, reproducibility\, and acquisiti
 on speed.\nA theoretical framework based on Fourier optics and k-space met
 hods was transferred to the acoustic domain\, enabling quantitative evalua
 tion of aperture geometry\, spatial bandwidth\, resolution\, and sampling 
 constraints. These considerations guided the development of a novel PZT pi
 ezo-fiber transducer with increased bandwidth\, larger opening angle\, and
  homogeneous 3D field characteristics. Semi-random sparse sampling strateg
 ies\, supported by compressive-sensing principles\, preserved imaging per
 formance despite sub-Nyquist sampling densities. Enhanced data-acquisition
  procedures with higher AScan counts enabled substantial SNR gains in refl
 ectivity reconstructions. To meet acquisition and excitation requirements\
 , a new µTCA-based data-acquisition system and a dedicated USCT ASIC were
  implemented\, significantly improving analog and digital performance.\nSt
 udies demonstrate improved illumination homogeneity\, approximately five-m
 inute acquisition time per breast\, enhanced bandwidth\, and increased SNR
  and dynamic range. Following initial clinical evaluation\, 3D USCT III ha
 s entered regulatory preparation for a multicenter trial\, representing a 
 substantial step toward routine clinical application of volumetric ultraso
 und tomography for early breast cancer detection.\n \n\nhttps://indico.ki
 t.edu/event/5652/
LOCATION:Seminarraum EG + zoom (IPE)
URL:https://indico.kit.edu/event/5652/
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