Oct 20 – 22, 2025
Karlsruhe Institute of Technology
Europe/Berlin timezone

Gas phase SAXS of protein complexes using our MS SPIDOC platform

Not scheduled
20m
Johann-Gottfried-Tulla-Hörsaal (Karlsruhe Institute of Technology)

Johann-Gottfried-Tulla-Hörsaal

Karlsruhe Institute of Technology

Englerstraße 11, 76131 Karlsruhe

Speaker

Thomas Kierspel

Description

MS SPIDOC is a novel sample delivery system for X-ray diffractive imaging at synchrotrons and X-ray Free-Electron Lasers. It accommodates biological samples ranging from small proteins to megadalton-scale particles. Using nano-electrospray ionization, ionic samples can be m/z-filtered and structurally separated prior to imaging. Here, we report the first SAXS data collected at the P12 EMBL beamline of PETRA III.

Author

Thomas Kierspel

Co-authors

Prof. Carl Caleman Charlotte Uetrecht Dr Clement Blanchet Dr Jocky Kung Tomislav Damjanovic

Presentation materials

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