Speaker
Description
FLASH radiotherapy has emerged as a promising approach for widening the therapeutic window of cancer treatment. Proton and carbon ion beams offer additional advantages through their superior dose localization and high dose conformity enabled by pencil beam scanning delivery.
However, synchrotron-based beams exhibit complex temporal structures, including variations in spill shape, extraction dynamics, and scanning patterns. These delivery characteristics directly influence dose-rate characterization and detector response, introducing additional challenges for reliable dosimetry under ultra-high dose-rate (UHDR) conditions. A delivery-aware dosimetric framework is therefore required to establish meaningful dose-rate metrics and appropriate measurement strategies for ion FLASH research and clinical implementation.
This work presents recent developments in a UHDR dosimetry framework dedicated to synchrotron-based proton and carbon ion beams. By connecting beam delivery physics, dosimetric measurements, and detector modelling, this work contributes to the development of clinically reliable ion FLASH therapy and provides practical tools for future research and clinical translation.